Yeast two-hybrid and in vivo studies demonstrate that jet binds to cry in a light-induced manner, and that jet deficiency leads to cry accumulation in fly heads and cultured cells (Peschel et al., 2009)
Indeed, GLS inhibitors have shown promising tumor-suppressive activities in preclinical models for 968 and bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide (BPTES), or even in clinical models for CB-839 [100,101]
Intriguingly, it was found that males, but not females, showed an UA-related enrichment of methylation sites in genes involved with neuroprotective pathways 63
Impact of single nucleotide polymorphisms (SNPs) in antioxidant-enzyme genes on the concentrations of folate, homocysteine and glutathione in plasma from healthy subjects after folic acid supplementation a randomized controlled crossover trial
RSC Adv The R Soc Chem (2024) 14:181321
Kwon H-B, Sabatini BL